Sam,
My main ‘ingredients’ are plastic card, Milliput epoxy putty, superglue, superglue accelerator and good references (scale drawings AND pictures).
By plastic card, I also include evergreen-type of products, though in effect most of what I use from that range is small diameter round sections and small dimension square-ish sections. Plastic card, I buy in sheets of 2 square meters and use anything from 0,10 thou to 0,40 thou.
Milliput, I mostly use to fill in holes to give strength to the master, but this is also my favourite sculpting material for figures and busts.
Superglue (and accelerator) is mostly used to fill in gaps. I do not have a lot of patience and I hate having to wait hours for traditional putty to dry. I tend to use superglue to stick things together too, but usually also dab in some liquid poly glue to achieve a more resistant bond.
Scale drawings are a good source of info, but take any two from different sources and you will find that there are several differences.. that’s where the pictures come in handy, to settle disputes. The pictures other main use to to have a better ‘3D’ understanding, thanks to the shadows cast by, or the light reflected off this or that part or area on the pictures.
I started scratchbuilding quite early, after having first tested my skills at a couple of conversions, then a couple of vacuformed kits; those did require that a lot of their vacuformed components be replaced by spare parts from injection-molded kits, or simply scratchbuilt. Even the main parts of those vacuformed kits also required quite a bit of work (I used to build 1/72 WWI aircraft then) and it did not take long for me to consider a full scratchbuilt given the unavailability of certain subjects and the work still required by vacuformed kits.
I did not start designing patterns until about 10 years later, first for a number of companies then for myself too. My interests had moved on to 1/72 - 1/76 AFVs by then. I worked that way for about 9 years before a break of almost a year when I just could not do it anymore, complete burnt out caused by the need to accept any commission to pay bills rather than enjoying scale modelling.. When I started my own company, I decided to only design stuff I was interested in. That made a huge difference! Nowadays, I still take on a commission time to time, but only on my terms, only things that interest me.
Most of the stuff I design is for the moment still relatively ‘safe’ from CAD and 3D-printing, but the technology is improving all the time, and fast.. That’s why I’m slowly getting involved too.